Synthesis of a potential redox active ligand for platinum complexes

Abstract

Redox active ligands can cooperate with the metal in a synergistic manner and their interplay facilitates the chemical process especially in the catalytic reactions. In this research, the ligand part has a quinoxaline structure. Quinoxaline compounds are essential nitrogen containing heterocyclic compounds of various biological properties (i.e. anti-tumor, anticancer) thus they have several pharmaceutical applications. It is also known that quinoxaline derivatives have a very wide range of applications in electrical and photochemical agents as well. The ligand has an extended {u1D70B} conjugated system, properties such as photoluminescence and fluorescence are expected to be observed. The yield optimization of two different functionalized quinoxalines as potential redox active ligands with air free conditions and syntheses of their platinum complexes were studied in this research. The goal of this study is to synthesize a platinum complex with redox active ligand. Coordination was observed from thermal, 1H NMR and fluorescence spectroscopic analyses for both of the complexes. Physical and chemical characterization of the synthesized ligands and complexes were determined via 1H and 13C NMR, DSC, fluorescent and UV-Vis spectrophotometer. It was shown that both of these ligands can act as ligands to transition metals the first example was with platinum.