Design of a dynamic optical property monitoring system: Studying the effect of temperature change

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Date

2018.

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Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2018.

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In laser applications, it is necessary to know the tissue optical properties before the treatment and how they change during the treatment. The optical monitoring system with double-integrating-sphere having a special sample heating apparatus was designed to investigate the e ect of temperature on optical properties. Temperature dependent optical property changes was investigated using lipid emulsion. It was found that the re ectance value showed negative correlation with temperature and transmittance showed positive correlation. Also, it was observed that the reduced scattering coe cient obtained using an inverse adding-doubling method showed a negative correlation with temperature, but there was no statistically signi cant change in absorption coe cient. The e ect of such optical property changes on the light propagation was displayed by Monte Carlo simulation. As a result, optical properties can change with temperature and this change must be taken into account for safer laser applications.|Keywords : Double-Integrating-Sphere, Temperature Effect, Optical Property, Monte Carlo Simulation.

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